Antihypertensive and Vasorelaxant Effect of Alstonia scholaris Stem Bark Extracts and Fractions
نویسندگان
چکیده
منابع مشابه
A Novel Steroid from Stem Bark of Alstonia Scholaris
A new steroid, 3-hydroxy adiantulanosterol (5), together with four known compounds, were isolated from the stem bark of Alstonia scholaris. All structures were elucidated by spectroscopic methods.
متن کاملPreliminary Physico-phytochemical Study of Stem Bark of Alstonia Scholaris (l.) R. Br. – a Medicinal Plant
Alstonia scholaris (L.) R. Br. is a plant of family Apocynaceae and has a great medicinal importance. It is widely used by tribal people to treat various diseases and ailments. The present communication deals with the organoleptic and preliminary physico-phytochemical studies of the stem bark of the plant. The organoleptic study was done according to the W.H.O. guidelines for medicinal plants. ...
متن کاملAcute and Sub-Acute Toxicity Evaluation of the Methanolic Extract of Alstonia scholaris Stem Bark
Alstonia scholaris has been used by traditional medicine practitioners since the medieval ages for the treatment of diseases. The aim of this research was to evaluate the acute and sub-acute oral toxicity of its methanolic extract. The acute toxicity test was conducted using Sprague Dawley (SD) rats. The methanolic extract of Alstonia scholaris stem bark (ASME) was administrated in a single dos...
متن کاملQuinine and Alstonia Scholaris (Chhatim) in Malaria
Recent work has shown that Alstonia scholaris has little or no antimalarial action on Plasmodia of birds (Goodson, Henry and Macfie, 1930 ; Buttle, cited by Sharp, 1934), monkeys and man (Mukerji, Ghosh and Siddons, 1942). These findings do not bear out those of earlier workers in the treatment of fevers believed to be of malarial origin. It was claimed that the alkaloids of Alstonia were more ...
متن کاملAntihypertensive, vasorelaxant, and antioxidant effect of root bark of Ulmus macrocarpa.
The present study was performed to evaluate the cardiovascular effects of ethanolic extract from the root bark of Ulmus macrocarpa (RBUM) in rats. The effects of RBUM on the vascular response of isolated rat aorta and the blood pressure of spontaneously hypertensive rats (SHRs) were evaluated. In addition, its antioxidant activity in H9c2 cells was investigated. In the free radical scavenging a...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2015
ISSN: 1811-7775
DOI: 10.3923/ijp.2015.327.334